Treatment and follow-up of children with transient congenital hypothyroidism

Treatment and follow-up of children with transient congenital hypothyroidism.

OBJECTIVE To study the clinical therapy and prognosis in children with transient congenital hypothyroidism (CH). METHODS Fifty-seven children with CH diagnosed after neonatal screening were treated with low-dosage levothyroxine (L-T4). Follow-up evaluation included the determination of TT3, TT4 and TSH serum levels and the assessment of thyroid gland morphology, bone age, growth development a...

Developmental Skills of Children with and Without Congenital Hypothyroidism

Background: Congenital hypothyroidism is one of the most common endocrinology diseases in children. Given the importance of evaluating the normal growth and development and identifying growth and development abnormalities, this study aimed to evaluate the developmental skills of patients with congenital hypothyroidism and healthy children. Materials and Methods: This controlled cross-sectional...

Follow-up of children with congenital clubfoot

Congenital urogenital abnormalities in children with congenital hypothyroidism

Background: Congenital hypothyroidism (CH), as one of the most common congenital endocrine disorders, may be significantly associated with congenital malformations. This study investigates urogenital abnormalities in children with primary CH (PCH). Methods: This case-control study was conducted on 200 children aged three months to 1 year, referred to Amir-Kabir Hospital, Arak, Iran. One hund...

Long term treatment of congenital hypothyroidism with L-triiodothyronine: 24 year follow-up.

A congenital hypothyroidism complicated by ventricular septal defects which was treated with L-triiodothyronine (L-T3) alone from 1 5/12 to 25 years, is described. The patient's growth and development was satisfactory and without side effects. It suggests that L-T3 may be a safe drug for long term treatment of congenital hypothyroidism.